NILE
CHEMICALS
NILE
CHEMICALS
1.
IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
1.1
Product identifiers
Product
name : 2-Nitroaniline
CAS-No.
: 88-74-4
2.
HAZARDS IDENTIFICATION
Classification
of the substance or mixture
Classification
according to Regulation (EC) No 1272/2008 [EU-GHS/CLP]
Acute
toxicity, Inhalation (Category 3)
Acute
toxicity, Dermal (Category 3)
Acute
toxicity, Oral (Category 3)
Specific
target organ toxicity - repeated exposure (Category 2)
Chronic
aquatic toxicity (Category 3)
Classification
according to EU Directives 67/548/EEC or 1999/45/EC
Toxic
by inhalation, in contact with skin and if swallowed. Danger of cumulative
effects. Harmful to aquatic
organisms,
may cause long-term adverse effects in the aquatic environment.
3.
COMPOSITION/INFORMATION ON INGREDIENTS
Substances
Formula
: C6H6N2O2
Molecular
Weight : 138,12 g/mol
Component
Concentration
o-Nitroaniline
CAS-No.
88-74-4
4.
FIRST AID MEASURES
Description
of first aid measures
General
advice Consult a physician. Show this
safety data sheet to the doctor in attendance.
If
inhaled If breathed in, move person into
fresh air. If not breathing, give artificial respiration. Consult a physician.
In
case of skin contact Wash off with soap and
plenty of water. Take victim immediately to hospital. Consult a physician.
In
case of eye contact Flush eyes with water
as a precaution.
If
swallowed Never give anything by mouth to
an unconscious person. Rinse mouth with water. Consult a physician.
Most
important symptoms and effects, both acute and delayed Absorption
into the body leads to the formation of methemoglobin which in sufficient
concentration causes
cyanosis.
Onset may be delayed 2 to 4 hours or longer., To the best of our knowledge, the
chemical,
physical,
and toxicological properties have not been thoroughly investigated.
Indication
of any immediate medical attention and special treatment needed no
data available
5.
FIRE-FIGHTING MEASURES
Extinguishing
media
Suitable
extinguishing media Use water spray,
alcohol-resistant foam, dry chemical or carbon dioxide.
Special
hazards arising from the substance or mixture Carbon
oxides, nitrogen oxides (NOx)
Advice
for firefighters Wear self contained
breathing apparatus for fire fighting if necessary.
Further
information no data available
6.
ACCIDENTAL RELEASE MEASURES
Personal
precautions, protective equipment and emergency procedures Wear
respiratory protection. Avoid dust formation. Avoid breathing vapors, mist or
gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid
breathing dust.
Environmental
precautions Prevent further leakage or
spillage if safe to do so. Do not let product enter drains. Discharge into the
environment
must be avoided.
Methods
and materials for containment and cleaning up
Pick
up and arrange disposal without creating dust. Sweep up and shovel. Keep in
suitable, closed
containers
for disposal.
Reference
to other sections For disposal see section
13.
7.
HANDLING AND STORAGE
Precautions
for safe handling Avoid contact with skin
and eyes. Avoid formation of dust and aerosols.
Provide
appropriate exhaust ventilation at places where dust is formed.Normal measures
for preventive fire
protection.
Conditions
for safe storage, including any incompatibilities Store
in cool place. Keep container tightly closed in a dry and well-ventilated place.
Light
sensitive.
Specific
end uses no data available
8.
EXPOSURE CONTROLS/PERSONAL PROTECTION
Control
parameters
Components
with workplace control parameters
Exposure
controls
Appropriate
engineering controls Avoid contact with
skin, eyes and clothing. Wash hands before breaks and immediately after handling
the
product.
Personal protective equipment
Eye/face
protection Face shield and safety glasses
Use equipment for eye protection tested and approved under
appropriate
government standards such as NIOSH (US) or EN 166(EU).
Skin
protection Handle with gloves. Gloves must
be inspected prior to use. Use proper glove removal technique
(without
touching glove's outer surface) to avoid skin contact with this product. Dispose
of
contaminated
gloves after use in accordance with applicable laws and good laboratory
practices.
Wash
and dry hands.
Body
Protection Complete suit protecting against
chemicals, The type of protective equipment must be selected
according
to the concentration and amount of the dangerous substance at the specific
workplace.
Respiratory
protection Where risk assessment shows
air-purifying respirators are appropriate use a full-face particle
respirator
type N99 (US) or type P2 (EN 143) respirator cartridges as a backup to
engineering
controls.
If the respirator is the sole means of protection, use a full-face supplied air
respirator. Use
respirators
and components tested and approved under appropriate government standards such
as
NIOSH
(US) or CEN (EU).
9.
PHYSICAL AND CHEMICAL PROPERTIES
Information
on basic physical and chemical properties
a)
Appearance Form: crystalline
b)
Odour no data available
c)
Odour Threshold no data available
d)
pH no data available
e)
Melting point/freezing point
Melting
point/range: 70 - 72 °C
Melting
point/range: 70 - 73 °C - lit.
f)
Initial boiling point and boiling range 284 °C - lit.
g)
Flash point 167,0 °C - closed cup
h)
Evaporation rate no data available
i)
Flammability (solid, gas) no data available
j)
Upper/lower flammability or explosive limits no data available
k)
Vapour pressure no data available
l)
Vapour density no data available
m)
Relative density no data available
n)
Water solubility no data available
o)
Partition coefficient: noctanol/water log Pow: 5
p)
Autoignition temperature no data available
q)
Decomposition temperature no data available
r)
Viscosity no data available
s)
Explosive properties no data available
t)
Oxidizing properties no data available
Other
safety information
no
data available
10.
STABILITY AND REACTIVITY
Reactivity
no data available
Chemical
stability no data available
Possibility
of hazardous reactions no data available
Conditions
to avoid no data available
Incompatible
materials Strong oxidizing agents
Hazardous
decomposition products Other decomposition
products - no data available
11.
TOXICOLOGICAL INFORMATION
Information
on toxicological effects
Acute
toxicity
LD50
Oral - rat - 1.600 mg/kg
Remarks:
Behavioral:Somnolence (general depressed activity). Behavioral:Convulsions or
effect on seizure
threshold.
LC50
Inhalation - rat - 4,0 h - > 2.554,29 mg/m3
Remarks:
Respiratory disorder Nutritional and Gross Metabolic:Weight loss or decreased
weight gain.
Nutritional
and Gross Metabolic:Changes in:Body temperature decrease.
Skin
corrosion/irritation no data available
Serious
eye damage/eye irritation no data available
Respiratory
or skin sensitization Prolonged or repeated
exposure may cause allergic reactions in certain sensitive individuals.
Germ
cell mutagenicity no data available
Carcinogenicity
IARC: No component of this product present
at levels greater than or equal to 0.1% is identified as
probable,
possible or confirmed human carcinogen by IARC.
Reproductive
toxicity no data available
Specific
target organ toxicity - single exposure no
data available
Specific
target organ toxicity - repeated exposure no
data available
Aspiration
hazard no data available
Potential
health effects Inhalation Harmful if
inhaled. May cause respiratory tract irritation.
Ingestion
Harmful if swallowed.
Skin
Toxic if absorbed through skin. May cause
skin irritation.
Eyes
May cause eye irritation.
Signs
and Symptoms of Exposure Absorption into
the body leads to the formation of methemoglobin which in sufficient
concentration causes
cyanosis.
Onset may be delayed 2 to 4 hours or longer., To the best of our knowledge, the
chemical,
physical,
and toxicological properties have not been thoroughly investigated.
Additional
Information RTECS: BY6650000
12.
ECOLOGICAL INFORMATION
Toxicity
Toxicity to daphnia and other aquatic
invertebrates.
Immobilization
EC50 - Daphnia magna (Water flea) - 4,89 mg/l - 48 h
Persistence
and degradability
Bioaccumulative
potential
Bioaccumulation
Danio rerio (zebra fish) - 96
h -0,028 mg/l
Bioconcentration
factor (BCF): 8,1
Mobility
in soil no data available
Results
of PBT and vPvB assessment no data
available
Other
adverse effects Toxic to aquatic life.
13.
DISPOSAL CONSIDERATIONS
Waste
treatment methods
Product
Offer surplus and non-recyclable solutions
to a licensed disposal company. Contact a licensed professional
waste
disposal service to dispose of this material. Dissolve or mix the material with
a combustible solvent
and
burn in a chemical incinerator equipped with an afterburner and scrubber.
Contaminated
packaging Dispose of as unused product.
14.
TRANSPORT INFORMATION
UN
number
ADR/RID:
1661 IMDG: 1661 IATA: 1661
UN
proper shipping name
ADR/RID:
NITROANILINES
IMDG:
NITROANILINES
IATA:
Nitroanilines
Transport
hazard class(es)
ADR/RID:
6.1 IMDG: 6.1 IATA: 6.1
Packaging
group
ADR/RID:
II IMDG: II IATA: II
Environmental
hazards
ADR/RID:
no IMDG Marine pollutant: no IATA: no
Special
precautions for user
no
data available
15.
REGULATORY INFORMATION
This
safety datasheet complies with the requirements of Regulation (EC) No.
1907/2006.
Safety,
health and environmental regulations/legislation specific for the substance or
mixture
no
data available
Chemical
Safety Assessment
no
data available
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