NILE CHEMICALS
Material Safety Data Sheet
Chloroform-d
MSDS
Section
1: Chemical Product and Company Identification
Product
Name: Chloroform-d "99.8%"
Catalog
Codes: SLC4681
CAS#:
865-49-6
RTECS:
FS9100000
TSCA:
TSCA
8(b) inventory: Chloroform-d "99.8%"
CI#:
Not
available.
Synonym:
Trichloromethane-d;
Methane-d, trichlor-
Chemical
Name: Chloroform-d "99.8%"
Chemical
Formula: CDCl3
Contact
Information: Nile Chemicals
CHEMTREC
(24HR Emergency Telephone), call: 1-800-424-9300
International
CHEMTREC, call: 1-703-527-3887
For
non-emergency assistance, call: 1-281-441-4400
Section
2: Composition and Information on Ingredients
Composition:
Name CAS #
% by Weight
Chloroform-d
"99.8%"
865-49-6
100
Toxicological
Data on Ingredients: Chloroform-d "99.8%": ORAL (LD50): Acute: 695
mg/kg [Rat]. 36 mg/kg
[Mouse].
DERMAL (LD50): Acute: >20000 mg/kg [Rabbit]. VAPOR (LC50): Acute: 47702
mg/m 4 hours [Rat].
Section
3: Hazards Identification
Potential
Acute Health Effects: Hazardous in case of skin
contact (irritant), of eye contact (irritant), of ingestion, of inhalation.
Slightly hazardous in case of skin contact (permeator).
Potential
Chronic Health Effects: CARCINOGENIC EFFECTS:
Classified A3 (Proven for animal.) by ACGIH. MUTAGENIC EFFECTS: Mutagenic for
mammalian somatic cells. Mutagenic for bacteria and/or yeast.
TERATOGENIC EFFECTS: Not available. DEVELOPMENTAL
TOXICITY:
Not available. The substance may be toxic to kidneys, liver, heart. Repeated
or prolonged exposure to the substance can produce target organs damage.
Section
4: First Aid Measures
Eye
Contact: Check for and remove any contact lenses. In case of contact,
immediately flush eyes with plenty of water for at least 15
minutes.
Cold water may be used. WARM water MUST be used. Get medical attention.
Skin
Contact: In case of contact, immediately flush skin with plenty of water.
Cover the irritated skin with an emollient. Remove contaminated clothing and
shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get
medical attention.
Serious
Skin Contact: Wash with a disinfectant soap and cover the contaminated skin with
an anti-bacterial cream. Seek immediate medical
attention.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. Get medical
attention.
Serious
Inhalation: Evacuate the victim to a safe area as soon as possible. Loosen
tight clothing such as a collar, tie, belt or waistband. If breathing is
difficult, administer oxygen. If the victim is not breathing, perform
mouth-to-mouth resuscitation. WARNING: It may be hazardous to the person
providing aid to give mouth-to-mouth resuscitation when the inhaled material
is toxic, infectious or
corrosive.
Seek medical attention.
Ingestion:
Do NOT induce vomiting unless directed to do so by medical
personnel. Never give anything by mouth to an unconscious person. If large
quantities of this material are swallowed, call a physician immediately.
Loosen tight clothing such as a collar, tie, belt or waistband.
Serious
Ingestion: Not available.
Section
5: Fire and Explosion Data
Flammability
of the Product: Non-flammable.
Auto-Ignition
Temperature: Not applicable.
Flash
Points: Not applicable.
Flammable
Limits: Not applicable.
Products
of Combustion: Not available.
Fire
Hazards in Presence of Various Substances: Not
applicable.
Explosion
Hazards in Presence of Various Substances:
Risks
of explosion of the product in presence of mechanical impact: Not available.
Risks of explosion of the product in
presence
of static discharge: Not available.
Fire
Fighting Media and Instructions: Not
applicable.
Special
Remarks on Fire Hazards: Not available.
Special
Remarks on Explosion Hazards:
M a y e
x p l o d e i f i t c o m e s i n c o n t a c t w i t h a l u m i n u m p o w
d e r , l i t h i u m , p e r c h l o r a t e , p e n t o x i d e ,
bis(dimethylamino)dimethylstannane, potassium, potassium-sodium alloy, sodium
(or sodium hydroxide or sodium methoxide), and methanol
Section
6: Accidental Release Measures
Small
Spill: Absorb with an inert material and put the spilled material in an
appropriate waste disposal.
Large
Spill:
Absorb
with an inert material and put the spilled material in an appropriate waste
disposal. Be careful that the product is not
present
at a concentration level above TLV. Check TLV on the MSDS and with local
authorities.
Section
7: Handling and Storage
Precautions:
Do not ingest. Do not breathe gas/fumes/ vapor/spray. Wear suitable
protective clothing. In case of insufficient ventilation, wear suitable
respiratory equipment. If ingested, seek medical advice immediately and show
the container or the label. Avoid contact
with skin and eyes. Keep away from incompatibles such as metals, alkalis.
Storage:
Keep
container tightly closed. Keep container in a cool, well-ventilated area.
Refrigerate. Do not store above 5°C (41°F). Store
at
temperatures from -5 C to 5 C. Sensitive to light. Store in light-resistant
containers.
Section
8: Exposure Controls/Personal Protection
Engineering
Controls:
Provide
exhaust ventilation or other engineering controls to keep the airborne
concentrations of vapors below their respective threshold limit value. Ensure
that eyewash stations and safety showers are proximal to the work-station
location.
Personal
Protection:
Splash
goggles. Lab coat. Vapor respirator. Be sure to use an approved/certified
respirator or equivalent. Gloves.
Personal
Protection in Case of a Large Spill:
Splash
goggles. Full suit. Vapor respirator. Boots. Gloves. A self contained
breathing apparatus should be used to avoid
inhalation of the product. Suggested protective clothing might not be
sufficient; consult a specialist BEFORE handling this product.
Exposure
Limits:
TWA: 10
(ppm) [Australia] Inhalation TWA: 2 (ppm) from OSHA (PEL) [United States]
Inhalation STEL: 9.78 (mg/m3) from
NIOSH
Inhalation STEL: 2 (ppm) from NIOSH Inhalation TWA: 9.78 (mg/m3) from OSHA
(PEL) [United States] Inhalation
TWA: 10
(ppm) from ACGIH (TLV) [United States] [1999] Inhalation TWA: 2 (ppm) [United
Kingdom (UK)] Inhalation TWA: 9.9
(mg/m3)
[United Kingdom (UK)] InhalationConsult local authorities for acceptable
exposure limits.
Section
9: Physical and Chemical Properties
Physical
state and appearance: Liquid.
Odor:
Pleasant.
Sweetish. Etheric. Non-irritating
Taste:
Burning.
Sweet.
Molecular
Weight: 120.38 g/mole
Color:
Colorless.
Clear
pH
(1% soln/water): Not available.
Boiling
Point: 61°C (141.8°F)
Melting
Point: -63.5°C (-82.3°F)
Critical
Temperature: 263.33°C (506°F)
Specific
Gravity: 1.484 (Water = 1)
Vapor
Pressure: 21.1 kPa (@ 20°C)
Vapor
Density: 4.36 (Air = 1)
Volatility:
Not available.
Odor
Threshold: 85 ppm
Water/Oil
Dist. Coeff.: The product is more soluble in oil; log(oil/water) = 2
Ionicity
(in Water): Not available.
Dispersion
Properties: Not available.
Solubility:
Very slightly soluble in cold water.
Section
10: Stability and Reactivity Data
Stability:
The product is stable.
Instability
Temperature: Not available.
Conditions
of Instability: Incompatible materials, light
Incompatibility
with various substances: Reactive with metals,
alkalis.
Corrosivity:
Non-corrosive in presence of glass.
Special
Remarks on Reactivity:
Light
Sensitive. Incompatible with triisopropyl phosphine, acetone, disilane,
fluorine, strong bases and reactive metals
(aluminum,
magnesium in powdered form), light.
Special
Remarks on Corrosivity: It will attack some forms
of plastics, rubber, and coatings.
Polymerization:
Will not occur.
Section
11: Toxicological Information
Routes
of Entry: Absorbed through skin. Eye contact. Inhalation.
Toxicity
to Animals:
WARNING:
THE LC50 VALUES HEREUNDER ARE ESTIMATED ON THE BASIS OF A 4-HOUR EXPOSURE.
Acute oral
toxicity
(LD50): 36 mg/kg [Mouse]. Acute dermal toxicity (LD50): >20000 mg/kg
[Rabbit]. Acute toxicity of the vapor (LC50):
47702
mg/m 4 hours [Rat]. 3
Chronic
Effects on Humans:
CARCINOGENIC
EFFECTS: Classified A3 (Proven for animal.) by ACGIH. MUTAGENIC EFFECTS:
Mutagenic for
mammalian
somatic cells. Mutagenic for bacteria and/or yeast. May cause damage to the
following organs: kidneys, liver,
heart.
Other
Toxic Effects on Humans:
Hazardous
in case of skin contact (irritant), of ingestion, of inhalation. Slightly
hazardous in case of skin contact (permeator).
Special
Remarks on Toxicity to Animals: Not available.
Special
Remarks on Chronic Effects on Humans:
May
affect genetic material (possible mutangen) and cause adverse reproductive
effects(embryotoxicity and fetotoxicity) Suspected carcinogen (tumorigenic)
and teratogen based on animal data. Human: passes the placental barrier,
detected in maternal milk.
Special
Remarks on other Toxic Effects on Humans:
Acute
Potential Health Effects: Skin: Causes skin irritation and may cause chemical
burns. Eye: Causes eye irritation, burning pain and reversible injury to
corneal epithelium. Inhalation: Causes irritation of the respiratory system
(mucous membranes). May affect behavior (Central Nervous system) - CNS
depressant, fatigue, dizziness, nausea, gidiness, euphoria, loss of
coordination and judgement, weakness, anorexia (neurological and
gastrointestinal symtoms resembling chronic alcoholism),
and
possibly coma and death. May affect the liver, kidneys and gastrointestinal
tract (nausea, vomiting). Ingestion: Causes gastrointestinal tract irritation
(nausea, vomiting). May affect the liver, urinary system, and heart. Chronic
Potential Health Effects: May affect the liver, heart and kidneys.
Section
12: Ecological Information
Ecotoxicity:
Not available.
BOD5
and COD: Not available.
Products
of Biodegradation:
Possibly
hazardous short term degradation products are not likely. However, long term
degradation products may arise.
Toxicity
of the Products of Biodegradation: The products
of degradation are less toxic than the product itself.
Special
Remarks on the Products of Biodegradation: Not
available.
Section
13: Disposal Considerations
Waste
Disposal:
Section
14: Transport Information
DOT
Classification: CLASS 6.1: Poisonous material.
Identification:
: Chloroform UNNA: 1888 PG: III
Special
Provisions for Transport: Not available.
Section
15: Other Regulatory Information
Federal
and State Regulations:
California
prop. 65: This product contains the following ingredients for which the State
of California has found to cause cancer,
birth
defects or other reproductive harm, which would require a warning under the
statute: Chloroform California prop. 65 (no
significant
risk level): Chloroform: 0.02 mg/day (value) California prop. 65: This product
contains the following ingredients for
which
the State of California has found to cause cancer which would require a
warning under the statute: Chloroform New
York
release reporting list: Chloroform Rhode Island RTK hazardous substances:
Chloroform Pennsylvania RTK: Chloroform
Massachusetts
RTK: Chloroform New Jersey: Chloroform California Director's List of Hazardous
Subtances (8 CCR 339):
Chloroform
Tennesse: Chloroform TSCA 8(b) inventory: Chloroform-d "99.8%" SARA
302/304/311/312 extremely hazardous
substances:
Chloroform SARA 313 toxic chemical notification and release reporting:
Chloroform CERCLA: Hazardous
substances.:
Chloroform: 10 lbs. (4.536 kg)
Other
Regulations:
OSHA:
Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).
EINECS: This product is on the
European
Inventory of Existing Commercial Chemical Substances.
Other
Classifications:
WHMIS
(Canada):
CLASS
D-1A: Material causing immediate and serious toxic effects (VERY TOXIC). CLASS
D-2A: Material causing other toxic
effects
(VERY TOXIC).
DSCL
(EEC):
R20/22-
Harmful by inhalation and if swallowed. R38- Irritating to skin. R40- Possible
risks of irreversible effects. S36/37- Wear
suitable
protective clothing and gloves.
HMIS
(U.S.A.):
Health
Hazard: 2
Fire
Hazard: 0
Reactivity:
0
Personal
Protection: h
National
Fire Protection Association (U.S.A.):
Health:
2
p. 6
Flammability:
0
Reactivity:
0
Specific
hazard:
Protective
Equipment:
Gloves.
Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or
equivalent. Wear appropriate respirator
when
ventilation is inadequate. Splash goggles.
Section
16: Other Information
The
information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no
liability resulting from its use. Users should make their own investigations
to determine the suitability of the information for their particular purposes.
In no event shall Nile Chemicals for any claims, losses, or damages of any
third party or for lost profits or any special, indirect, incidental,
consequential or exemplary damages, howsoever arising, even if Nile Chemicals has been
advised of the possibility of such damages.
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