NILE CHEMICALS

                         Material Safety Data Sheet
 
Chloroform-d  MSDS
 
Section 1: Chemical Product and Company Identification
Product Name: Chloroform-d "99.8%"
Catalog Codes: SLC4681
CAS#: 865-49-6
RTECS: FS9100000
TSCA: TSCA 8(b) inventory: Chloroform-d "99.8%"
CI#: Not available.
Synonym: Trichloromethane-d; Methane-d, trichlor-
Chemical Name: Chloroform-d "99.8%"
Chemical Formula: CDCl3
Contact Information: Nile Chemicals
 CHEMTREC (24HR Emergency Telephone), call: 1-800-424-9300
International CHEMTREC, call: 1-703-527-3887
For non-emergency assistance, call: 1-281-441-4400
 
Section 2: Composition and Information on Ingredients
Composition:                           Name CAS #                        % by Weight
Chloroform-d "99.8%"                   865-49-6                                100
Toxicological Data on Ingredients: Chloroform-d "99.8%": ORAL (LD50): Acute: 695 mg/kg [Rat]. 36 mg/kg
[Mouse]. DERMAL (LD50): Acute: >20000 mg/kg [Rabbit]. VAPOR (LC50): Acute: 47702 mg/m 4 hours [Rat].
 
Section 3: Hazards Identification
Potential Acute Health Effects: Hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. Slightly hazardous in case of skin contact (permeator).
Potential Chronic Health Effects: CARCINOGENIC EFFECTS: Classified A3 (Proven for animal.) by ACGIH. MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. Mutagenic for bacteria and/or yeast.  TERATOGENIC EFFECTS: Not available. DEVELOPMENTAL
TOXICITY: Not available. The substance may be toxic to kidneys, liver, heart. Repeated or prolonged exposure to the substance can produce target organs damage.
 
Section 4: First Aid Measures
Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Cold water may be used. WARM water MUST be used. Get medical attention.
Skin Contact: In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention.
Serious Skin Contact: Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate medical
attention.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical
attention.
Serious Inhalation: Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or waistband. If breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth resuscitation. WARNING: It may be hazardous to the person providing aid to give mouth-to-mouth resuscitation when the inhaled material is toxic, infectious or
corrosive. Seek medical attention.
Ingestion: Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or waistband.
Serious Ingestion: Not available.
 
Section 5: Fire and Explosion Data
Flammability of the Product: Non-flammable.
Auto-Ignition Temperature: Not applicable.
Flash Points: Not applicable.
Flammable Limits: Not applicable.
Products of Combustion: Not available.
Fire Hazards in Presence of Various Substances: Not applicable.
Explosion Hazards in Presence of Various Substances:
Risks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product in
presence of static discharge: Not available.
Fire Fighting Media and Instructions: Not applicable.
Special Remarks on Fire Hazards: Not available.
Special Remarks on Explosion Hazards:
M a y e x p l o d e i f i t c o m e s i n c o n t a c t w i t h a l u m i n u m p o w d e r , l i t h i u m , p e r c h l o r a t e , p e n t o x i d e , bis(dimethylamino)dimethylstannane, potassium, potassium-sodium alloy, sodium (or sodium hydroxide or sodium methoxide), and methanol
 
Section 6: Accidental Release Measures
Small Spill: Absorb with an inert material and put the spilled material in an appropriate waste disposal.
Large Spill:
Absorb with an inert material and put the spilled material in an appropriate waste disposal. Be careful that the product is not
present at a concentration level above TLV. Check TLV on the MSDS and with local authorities.
 
 
Section 7: Handling and Storage
Precautions: Do not ingest. Do not breathe gas/fumes/ vapor/spray. Wear suitable protective clothing. In case of insufficient ventilation, wear suitable respiratory equipment. If ingested, seek medical advice immediately and show the container or the label. Avoid  contact with skin and eyes. Keep away from incompatibles such as metals, alkalis.
Storage: Keep container tightly closed. Keep container in a cool, well-ventilated area. Refrigerate. Do not store above 5°C (41°F). Store
at temperatures from -5 C to 5 C. Sensitive to light. Store in light-resistant containers.
 
Section 8: Exposure Controls/Personal Protection
Engineering Controls:
Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their respective threshold limit value. Ensure that eyewash stations and safety showers are proximal to the work-station location.
 
Personal Protection:
Splash goggles. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.
 
Personal Protection in Case of a Large Spill:
Splash goggles. Full suit. Vapor respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid  inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product.
Exposure Limits:
TWA: 10 (ppm) [Australia] Inhalation TWA: 2 (ppm) from OSHA (PEL) [United States] Inhalation STEL: 9.78 (mg/m3) from
NIOSH Inhalation STEL: 2 (ppm) from NIOSH Inhalation TWA: 9.78 (mg/m3) from OSHA (PEL) [United States] Inhalation
TWA: 10 (ppm) from ACGIH (TLV) [United States] [1999] Inhalation TWA: 2 (ppm) [United Kingdom (UK)] Inhalation TWA: 9.9
(mg/m3) [United Kingdom (UK)] InhalationConsult local authorities for acceptable exposure limits.
 
Section 9: Physical and Chemical Properties
Physical state and appearance: Liquid.
Odor: Pleasant. Sweetish. Etheric. Non-irritating
Taste: Burning. Sweet.
Molecular Weight: 120.38 g/mole
Color: Colorless. Clear
pH (1% soln/water): Not available.
Boiling Point: 61°C (141.8°F)
Melting Point: -63.5°C (-82.3°F)
Critical Temperature: 263.33°C (506°F)
Specific Gravity: 1.484 (Water = 1)
Vapor Pressure: 21.1 kPa (@ 20°C)
Vapor Density: 4.36 (Air = 1)
Volatility: Not available.
Odor Threshold: 85 ppm
Water/Oil Dist. Coeff.: The product is more soluble in oil; log(oil/water) = 2
Ionicity (in Water): Not available.
Dispersion Properties: Not available.
Solubility: Very slightly soluble in cold water.
 
Section 10: Stability and Reactivity Data
Stability: The product is stable.
Instability Temperature: Not available.
Conditions of Instability: Incompatible materials, light
Incompatibility with various substances: Reactive with metals, alkalis.
Corrosivity: Non-corrosive in presence of glass.
Special Remarks on Reactivity:
Light Sensitive. Incompatible with triisopropyl phosphine, acetone, disilane, fluorine, strong bases and reactive metals
(aluminum, magnesium in powdered form), light.
Special Remarks on Corrosivity: It will attack some forms of plastics, rubber, and coatings.
Polymerization: Will not occur.
 
Section 11: Toxicological Information
Routes of Entry: Absorbed through skin. Eye contact. Inhalation.
Toxicity to Animals:
WARNING: THE LC50 VALUES HEREUNDER ARE ESTIMATED ON THE BASIS OF A 4-HOUR EXPOSURE. Acute oral
toxicity (LD50): 36 mg/kg [Mouse]. Acute dermal toxicity (LD50): >20000 mg/kg [Rabbit]. Acute toxicity of the vapor (LC50):
47702 mg/m 4 hours [Rat]. 3
 
Chronic Effects on Humans:
CARCINOGENIC EFFECTS: Classified A3 (Proven for animal.) by ACGIH. MUTAGENIC EFFECTS: Mutagenic for
mammalian somatic cells. Mutagenic for bacteria and/or yeast. May cause damage to the following organs: kidneys, liver,
heart.
 
Other Toxic Effects on Humans:
Hazardous in case of skin contact (irritant), of ingestion, of inhalation. Slightly hazardous in case of skin contact (permeator).
 
Special Remarks on Toxicity to Animals: Not available.
Special Remarks on Chronic Effects on Humans:
May affect genetic material (possible mutangen) and cause adverse reproductive effects(embryotoxicity and fetotoxicity) Suspected carcinogen (tumorigenic) and teratogen based on animal data. Human: passes the placental barrier, detected in maternal milk.
 
Special Remarks on other Toxic Effects on Humans:
Acute Potential Health Effects: Skin: Causes skin irritation and may cause chemical burns. Eye: Causes eye irritation, burning pain and reversible injury to corneal epithelium. Inhalation: Causes irritation of the respiratory system (mucous membranes). May affect behavior (Central Nervous system) - CNS depressant, fatigue, dizziness, nausea, gidiness, euphoria, loss of coordination and judgement, weakness, anorexia (neurological and gastrointestinal symtoms resembling chronic alcoholism),
and possibly coma and death. May affect the liver, kidneys and gastrointestinal tract (nausea, vomiting). Ingestion: Causes gastrointestinal tract irritation (nausea, vomiting). May affect the liver, urinary system, and heart. Chronic Potential Health Effects: May affect the liver, heart and kidneys.
 
Section 12: Ecological Information
Ecotoxicity: Not available.
BOD5 and COD: Not available.
Products of Biodegradation:
Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.
Toxicity of the Products of Biodegradation: The products of degradation are less toxic than the product itself.
Special Remarks on the Products of Biodegradation: Not available.
 
Section 13: Disposal Considerations
Waste Disposal:
 
Section 14: Transport Information
 
DOT Classification: CLASS 6.1: Poisonous material.
 
Identification: : Chloroform UNNA: 1888 PG: III
 
Special Provisions for Transport: Not available.
 
Section 15: Other Regulatory Information
Federal and State Regulations:
California prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer,
birth defects or other reproductive harm, which would require a warning under the statute: Chloroform California prop. 65 (no
significant risk level): Chloroform: 0.02 mg/day (value) California prop. 65: This product contains the following ingredients for
which the State of California has found to cause cancer which would require a warning under the statute: Chloroform New
York release reporting list: Chloroform Rhode Island RTK hazardous substances: Chloroform Pennsylvania RTK: Chloroform
Massachusetts RTK: Chloroform New Jersey: Chloroform California Director's List of Hazardous Subtances (8 CCR 339):
Chloroform Tennesse: Chloroform TSCA 8(b) inventory: Chloroform-d "99.8%" SARA 302/304/311/312 extremely hazardous
substances: Chloroform SARA 313 toxic chemical notification and release reporting: Chloroform CERCLA: Hazardous
substances.: Chloroform: 10 lbs. (4.536 kg)
Other Regulations:
OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200). EINECS: This product is on the
European Inventory of Existing Commercial Chemical Substances.
Other Classifications:
WHMIS (Canada):
CLASS D-1A: Material causing immediate and serious toxic effects (VERY TOXIC). CLASS D-2A: Material causing other toxic
effects (VERY TOXIC).
DSCL (EEC):
R20/22- Harmful by inhalation and if swallowed. R38- Irritating to skin. R40- Possible risks of irreversible effects. S36/37- Wear
suitable protective clothing and gloves.
HMIS (U.S.A.):
Health Hazard: 2
Fire Hazard: 0
Reactivity: 0
Personal Protection: h
National Fire Protection Association (U.S.A.):
Health: 2
p. 6
Flammability: 0
Reactivity: 0
Specific hazard:
Protective Equipment:
Gloves. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Wear appropriate respirator
when ventilation is inadequate. Splash goggles.
 
Section 16: Other Information
 
The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume  no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Nile Chemicals for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Nile Chemicals has been advised of the possibility of such damages.

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