NILE
CHEMICALS
SAFETY DATA SHEET
1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
1.1 Product identifiers
Product name : 4-Aminoacetanilide
Product Number : AP17
Brand : Nile
CAS-No. : 122-80-5
1.2 Relevant identified uses of the substance or mixture and uses advised
against
Identified uses : Laboratory chemicals, Manufacture of substances
1.3 Details of the supplier of the safety data sheet
Company : Nile Chemicals
Masjid Bundar
Mumbai 400009
INDIA
Telephone : +91 022-66313162
Fax : +91 022-23454828
2. HAZARDS IDENTIFICATION
2.1 Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP]
Eye irritation (Category 2)
Respiratory sensitization (Category 1)
Skin sensitization (Category 1)
Classification according to EU Directives 67/548/EEC or 1999/45/EC
Irritating to eyes. May cause sensitization by inhalation and skin contact.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008 [CLP]
Pictogram
Signal word Danger
Hazard statement(s)
H317 May cause an allergic skin reaction.
H319 Causes serious eye irritation.
H334 May cause allergy or asthma symptoms or breathing difficulties if
inhaled.
Precautionary statement(s)
P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
P280 Wear protective gloves.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several
minutes. Remove
contact lenses, if present and easy to do. Continue rinsing.
P342 + P311 If experiencing respiratory symptoms: Call a POISON CENTER or
doctor/
physician.
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Supplemental Hazard
Statements
none
According to European Directive 67/548/EEC as amended.
Hazard symbol(s)
R-phrase(s)
R36 Irritating to eyes.
R42/43 May cause sensitization by inhalation and skin contact.
S-phrase(s)
S22 Do not breathe dust.
S26 In case of contact with eyes, rinse immediately with plenty of water and
seek medical advice.
S36/37 Wear suitable protective clothing and gloves.
2.3 Other hazards - none
3. COMPOSITION/INFORMATION ON INGREDIENTS
3.1 Substances
Synonyms : N-(4-Aminophenyl)acetamide
N-Acetyl-p-phenylenediamine
Formula : C8H10N2O
Molecular Weight : 150,18 g/mol
Component Concentration
4'-Aminoacetanilide
CAS-No.
EC-No.
122-80-5
204-576-6
-
4. FIRST AID MEASURES
4.1 Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial
respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a
physician.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water.
Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
To the best of our knowledge, the chemical, physical, and toxicological
properties have not been
thoroughly investigated.
4.3 Indication of any immediate medical attention and special treatment needed
no data available
5. FIREFIGHTING MEASURES
5.1 Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Page 3 of 7
5.2 Special hazards arising from the substance or mixture
Carbon oxides, nitrogen oxides (NOx)
5.3 Advice for firefighters
Wear self contained breathing apparatus for fire fighting if necessary.
5.4 Further information
no data available
6. ACCIDENTAL RELEASE MEASURES
6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing
vapors, mist or gas. Ensure
adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.
6.2 Environmental precautions
Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep
in suitable, closed
containers for disposal.
6.4 Reference to other sections
For disposal see section 13.
7. HANDLING AND STORAGE
7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
Provide appropriate exhaust ventilation at places where dust is formed.Normal
measures for preventive fire
protection.
7.2 Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and
well-ventilated place.
7.3 Specific end uses
no data available
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
8.1 Control parameters
Components with workplace control parameters
8.2 Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash
hands before breaks and
at the end of workday.
Personal protective equipment
Eye/face protection
Face shield and safety glasses Use equipment for eye protection tested and
approved under
appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove
removal technique
(without touching glove's outer surface) to avoid skin contact with this
product. Dispose of
contaminated gloves after use in accordance with applicable laws and good
laboratory practices.
Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU
Directive 89/686/EEC and
the standard EN 374 derived from it.
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: > 480 min
Page 4 of 7
Material tested:DermatrilŪ (Aldrich Z677272, Size M)
Splash protection
Material: Nitrile rubber
Minimum layer thickness: 0,11 mm
Break through time: > 30 min
Material tested:DermatrilŪ (Aldrich Z677272, Size M)
data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail
sales@kcl.de,
test method: EN374
If used in solution, or mixed with other substances, and under conditions
which differ from EN 374,
contact the supplier of the CE approved gloves. This recommendation is
advisory only and must
be evaluated by an Industrial Hygienist familiar with the specific situation
of anticipated use by our
customers. It should not be construed as offering an approval for any specific
use scenario.
Body Protection
Complete suit protecting against chemicals, The type of protective equipment
must be selected
according to the concentration and amount of the dangerous substance at the
specific workplace.
Respiratory protection
For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle
respirator.For higher
level protection use type OV/AG/P99 (US) or type ABEK-P2 (EU EN 143)
respirator cartridges.
Use respirators and components tested and approved under appropriate
government standards
such as NIOSH (US) or CEN (EU).
9. PHYSICAL AND CHEMICAL PROPERTIES
9.1 Information on basic physical and chemical properties
a) Appearance Form: crystalline
Colour: light red
b) Odour no data available
c) Odour Threshold no data available
d) pH no data available
e) Melting point/freezing
point
Melting point/range: 164 - 167 °C - lit.
f) Initial boiling point and
boiling range
no data available
g) Flash point 150 °C - closed cup
h) Evaporation rate no data available
i) Flammability (solid, gas) no data available
j) Upper/lower
flammability or
explosive limits
no data available
k) Vapour pressure no data available
l) Vapour density no data available
m) Relative density no data available
n) Water solubility no data available
o) Partition coefficient: noctanol/
water
no data available
p) Autoignition
temperature
no data available
q) Decomposition
temperature
no data available
r) Viscosity no data available
Aldrich - 100528
Page 5 of 7
s) Explosive properties no data available
t) Oxidizing properties no data available
9.2 Other safety information
no data available
10. STABILITY AND REACTIVITY
10.1 Reactivity
no data available
10.2 Chemical stability
no data available
10.3 Possibility of hazardous reactions
no data available
10.4 Conditions to avoid
no data available
10.5 Incompatible materials
Strong oxidizing agents
10.6 Hazardous decomposition products
Other decomposition products - no data available
11. TOXICOLOGICAL INFORMATION
11.1 Information on toxicological effects
Acute toxicity
LD50 Oral - rat - 2.500 mg/kg
Skin corrosion/irritation
Serious eye damage/eye irritation
Eyes - rabbit - Moderate eye irritation - 24 h
Respiratory or skin sensitization
no data available
May cause allergic respiratory and skin reactions
Germ cell mutagenicity
no data available
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to
0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
no data available
Specific target organ toxicity - single exposure
no data available
Specific target organ toxicity - repeated exposure
no data available
Aspiration hazard
no data available
Potential health effects
Inhalation May be harmful if inhaled.
May cause respiratory tract irritation.
Ingestion May be harmful if swallowed.
Skin May be harmful if absorbed through
skin. May cause skin irritation.
Eyes Causes serious eye irritation.
Page 6 of 7
Signs and Symptoms of Exposure
To the best of our knowledge, the chemical, physical, and toxicological
properties have not been
thoroughly investigated.
Additional Information
RTECS: AD8225000
12. ECOLOGICAL INFORMATION
12.1 Toxicity
no data available
12.2 Persistence and degradability
no data available
12.3 Bioaccumulative potential
no data available
12.4 Mobility in soil
no data available
12.5 Results of PBT and vPvB assessment
no data available
12.6 Other adverse effects
no data available
13. DISPOSAL CONSIDERATIONS
13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.
Contact a licensed
professional waste disposal service to dispose of this material. Dissolve or
mix the material with a
combustible solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber.
Contaminated packaging
Dispose of as unused product.
14. TRANSPORT INFORMATION
14.1 UN number
ADR/RID: - IMDG: - IATA: -
14.2 UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods
14.3 Transport hazard class(es)
ADR/RID: - IMDG: - IATA: -
14.4 Packaging group
ADR/RID: - IMDG: - IATA: -
14.5 Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
14.6 Special precautions for user
no data available
15. REGULATORY INFORMATION
This safety datasheet complies with the requirements of Regulation (EC) No.
1907/2006.
15.1 Safety, health and environmental regulations/legislation specific for the
substance or mixture
no data available
15.2 Chemical Safety Assessment
no data available
Aldrich - 100528
Page 7 of 7
16. OTHER INFORMATION
Further information
The above information is believed to be correct but does not purport to be all
inclusive and shall be
used only as a guide. The information in this document is based on the present
state of our knowledge
and is applicable to the product with regard to appropriate safety
precautions. It does not represent any
guarantee of the properties of the product. Nile
Chemicals and its Affiliates shall not be
held
liable for any damage resulting from handling or from contact with the above
product.
the reverse side of invoice or packing slip for additional terms and
conditions of sale.
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