NILE
CHEMICALS
NILE
CHEMICALS
Section 1: Chemical Product and Company Identification
Product Name: Quinoline
Yellow
CAS#: 8004-92-0
Synonym: Quinoline
Yellow For Microscopy , C.I. 4700; D & C Yellow No. 11; C.I. Solvent Yellow
33; 1,3-Isobenzofurandione
Chemical Name: Solvent Yellow 33
Chemical
Formula: C18-H11-N-O2
Section 2: Composition and Information on Ingredients Composition:
Name CAS # % by Weight
Quinoline Yellow For Microscopy 8004-92-0 100
Toxicological Data on Ingredients: Quinoline
Yellow For Microscopy : DERMAL (LD50): Acute: >2000 mg/kg [Rabbit].
Section 3: Hazards Identification
Potential Acute Health Effects: Hazardous in case of skin contact (irritant), of eye contact
(irritant), of ingestion, of inhalation.
Potential Chronic Health Effects:
CARCINOGENIC EFFECTS: Not available. MUTAGENIC EFFECTS: Mutagenic
for mammalian somatic cells. Mutagenic for bacteria and/or yeast. TERATOGENIC
EFFECTS: Not available. DEVELOPMENTAL TOXICITY: Classified Reproductive
system/toxin/male [POSSIBLE]. The substance may be toxic to kidneys, liver.
Repeated or prolonged exposure to the substance can produce target organs
damage.
Section 4: First Aid Measures Eye Contact:
Check for and remove any contact lenses. In case of contact,
immediately flush eyes with plenty of water for at least 15 minutes. Get medical
attention.
Skin Contact: In
case of contact, immediately flush skin with plenty of water. Cover the
irritated skin with an emollient. Remove contaminated clothing and shoes. Wash
clothing before reuse. Thoroughly clean shoes before reuse. Get medical
attention.
Serious Skin Contact: Wash with a disinfectant soap and cover the contaminated skin with
an anti-bacterial cream. Seek immediate medical attention.
Inhalation: If
inhaled, remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Get medical attention.
Serious Inhalation: Not available.
Ingestion: Do
NOT induce vomiting unless directed to do so by medical personnel. Never give
anything by mouth to an unconscious person. If large quantities of this material
are swallowed, call a physician immediately. Loosen tight clothing such as a
collar, tie, belt or waistband.
Serious Ingestion: Not available.
Section 5: Fire and Explosion Data
Flammability of the Product: May be combustible at high temperature.
Auto-Ignition Temperature: Not available.
Flash Points: CLOSED
CUP: Higher than 93.3°C (200°F).
Flammable Limits: Not available.
Products of Combustion: These products are carbon oxides (CO, CO2), nitrogen oxides (NO,
NO2...).
Fire Hazards in Presence of Various Substances:
Slightly flammable to flammable in presence of open flames and
sparks, of heat. Non-flammable in presence of shocks.
Explosion Hazards in Presence of Various Substances:
Risks of explosion of the product in presence of mechanical impact:
Not available. Risks of explosion of the product in presence of static
discharge: Not available.
Fire Fighting Media and Instructions:
SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray,
fog or foam. Do not use water jet.
Special Remarks on Fire Hazards: Not
available.
Special Remarks on Explosion Hazards: Not
available.
Section 6: Accidental Release Measures Small Spill:
Use appropriate tools to put the spilled solid in a convenient
waste disposal container. Finish cleaning by spreading water on the contaminated
surface and dispose of according to local and regional authority requirements.
Large Spill: Use
a shovel to put the material into a convenient waste disposal container. Finish
cleaning by spreading water on the contaminated
surface and allow to evacuate through the sanitary system.
Section 7: Handling and Storage Precautions:
Keep locked up.. Keep away from heat. Keep away from sources of
ignition. Empty containers pose a fire risk, evaporate the residue under a fume
hood. Ground all equipment containing material. Do not ingest. Do not breathe
dust. Wear suitable protective clothing. In case of insufficient ventilation,
wear suitable respiratory equipment. If ingested, seek medical advice
immediately and show the container or the label. Avoid contact with skin and
eyes. Keep away from incompatibles such as oxidizing agents.
Storage: Keep
container tightly closed. Keep container in a cool, well-ventilated area. Do not
store above 23°C (73.4°F).
Section 8: Exposure Controls/Personal Protection Engineering
Controls:
Use process enclosures, local exhaust ventilation, or other
engineering controls to keep airborne levels below recommended exposure limits.
If user operations generate dust, fume or mist, use ventilation to keep exposure
to airborne contaminants below the exposure limit.
Personal Protection: Splash goggles. Lab coat. Dust respirator. Be sure to use an
approved/certified respirator or equivalent. Gloves.
Personal Protection in Case of a Large Spill: Splash
goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing
apparatus should be used to avoid inhalation of the product. Suggested
protective clothing might not be sufficient; consult a specialist BEFORE
handling this product.
Exposure Limits: Not available.
Section 9: Physical and Chemical Properties
Physical state and appearance: Solid. (Powdered solid.)
Odor: Not
available.
Taste: Not
available.
Molecular Weight: 273.29 g/mole
Color: Yellow.
pH (1% soln/water): Not available.
Boiling Point: Not available.
Melting Point: Not available.
Critical Temperature: Not available.
Specific Gravity: Not available.
Vapor Pressure: Not applicable.
Vapor Density: Not available.
Volatility: Not
available.
Odor Threshold: Not available.
Water/Oil Dist. Coeff.: Not available.
Ionicity (in Water): Not available.
Dispersion Properties: Not available.
Solubility: Not
available.
Section 10: Stability and Reactivity Data
Stability: The
product is stable.
Instability Temperature: Not available.
Conditions of Instability: Excess heat, dust generation, incompatiblematerials
Incompatibility with various substances: Reactive
with oxidizing agents.
Corrosivity: Not
available.
Special Remarks on Reactivity: Not available.
Special Remarks on Corrosivity: Not available.
Polymerization: Will not occur.
Section 11: Toxicological Information
Routes of Entry: Inhalation. Ingestion.
Toxicity to Animals: Acute dermal toxicity (LD50): >2000 mg/kg [Rabbit].
Chronic Effects on Humans: MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. Mutagenic
for bacteria and/or yeast. DEVELOPMENTAL TOXICITY: Classified Reproductive
system/toxin/male [POSSIBLE]. May cause damage to the following organs: kidneys,
liver.
Other Toxic Effects on Humans: Hazardous in case of skin contact (irritant), of ingestion,
of inhalation.
Special Remarks on Toxicity to Animals: LDL
[Rabbit] - Route: Oral; Dose: 5000 mg/kg
Special Remarks on Chronic Effects on Humans: May
cause adverse reproductive effects (male fertility, newborn growth/reduced
weight gain) based on animal data. May affect
genetic material (mutagen). May cause cancer (tumorigenic) based on
animal data.
Special Remarks on other Toxic Effects on Humans: Acute
Potential Health Effects: Skin: May cause skin irritation. May be harmful if
absorbed through skin. May affect liver, gastrointestinal tract, urinary system.
Eyes: May cause eye irritation. Inhalation: May cause respiratory tract and
mucous membrane irritation. May be harmful if inhaled. May affect metabolism and
respiration (structural or functional changes in trachea or bronchi). Ingestion:
May be harmful if swallowed. May cause irritation of the gastrointestinal
(digestive) tract. May affect urinary system and liver.
Section 12: Ecological Information
Ecotoxicity: Not
available.
BOD5 and COD: Not
available.
Products of Biodegradation:
Possibly hazardous short term degradation products are not likely.
However, long term degradation products may arise.
Toxicity of the Products of Biodegradation: The
products of degradation are less toxic than the product itself.
Special Remarks on the Products of Biodegradation: Not
available.
Section 13: Disposal Considerations
Waste Disposal:
Waste must be disposed of in accordance with federal, state and
local environmental control regulations.
Section 14: Transport Information
DOT Classification: Not a DOT controlled material (United States).
Identification: Not applicable.
Special Provisions for Transport: Not
applicable.
Section 15: Other Regulatory Information
Federal and State Regulations:
TSCA 8(b) inventory: Quinoline Yellow For Microscopy SARA 313
toxic chemical notification and release reporting: Quinoline Yellow For
Microscopy
Other Regulations: OSHA: Hazardous by definition of Hazard Communication Standard (29
CFR 1910.1200). EINECS: This product is on the European Inventory of Existing
Commercial Chemical Substances.
Other Classifications: WHMIS (Canada): Not
controlled under WHMIS (Canada).
DSCL (EEC): R20/21-
Harmful by inhalation and in contact with skin. R33- Danger of cumulative
effects. S2- Keep out of the reach of children. S36- Wear suitable protective
clothing. S46- If swallowed, seek medical advice immediately and show this
container or label.
HMIS (U.S.A.):
Health Hazard: 2
Fire Hazard: 1
Reactivity: 0
Personal Protection: E
National Fire Protection Association (U.S.A.):
Health: 1
Protective Equipment: Gloves. Lab coat. Dust respirator. Be sure to use an
approved/certified respirator or equivalent. Splash goggles.
NILE CEHMCIALS provides the information contained herein
in good faith but makes no representation as to its comprehensiveness or
accuracy. This document is intended only as a guide to the appropriate
precautionary handling of the material by a properly trained person using this
product. Individuals receiving the information must exercise their independent
judgment in determining its appropriateness for a particular purpose. NILE
CHEMICALS MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED,
INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A
PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE
PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, NILE CHEMICALS WILL NOT BE
RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
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